Location:
Genome Engineering of Algae

GeneRulor Gene Editing Platform


As one of the most ancient, fast-propagating and abundant microbial resources on Earth, algae boast unique advantages including high photosynthetic efficiency, strong   environmental adaptability and low cultivation cost. They possess irreplaceable and broad application prospects in food processing, pharmaceutical research and development, new energy development, environmental protection and other fields. Focusing on the core segment of algal gene editing, Generulor add ressesthe industry pain points of traditional algae cultivation, such as long breeding cycles, unstable characteristics and insufficient value exploitation. Relying on independently developed core technologies, the company optimizes thegrowth characteristics and metabolic pathways of algae through precise genetic modification, efficiently taps the potential value of algal resources, facilitates the efficient transformation of algal resources from basicscientific research to industrial application, and promotes the high-quality development of the algal biotechnology industry.

Core Gene Editing Strategies

Centered on technological innovation, Generulor has established a dual gene editing strategy integrating standardization and customization to adapt to diverse algal strains andcustomer demands. We adopt an independently developed CRISPR editing tool exclusively for algae with complete intellectual property rights, coupled withan optimized, safe and efficient gene delivery system, which effectively solves the challenges of traditional editing tools including poor adaptability, low delivery efficiency and unstable editing outcomes. In view of the genetic sequence characteristics of different algae such as prokaryotic algae and eukaryotic algae, we can efficiently fulfill various editing requirements including gene knockout, gene knock-in, site-directed mutagenesis and gene silencing, with an editing efficiency of over 95%. Meanwhile, relying on aproprietary off-target detection technology, we achieve precise editing with an off-target rate approaching zero. Furthermore, assisted by a high-throughput strainscreening platform, we can rapidly select positively edited strains, significantly shorten project cycles, balance editing precision and project progress efficiency, and comprehensively guarantee the stability and reliability of editing results.

Our Core Competitiveness

(1) Full technological coverage: Covering prokaryotic/eukaryotic algae and multi-genome editing to meet the differentiated demands of various customers;

(2) High precision and efficiency: Boastingan editing efficiency of up to 95% and an off-target rate approaching zero, and enabling rapid screening of positive strains with the support of the high-through put screening platform;

(3) Controllable cost: Providing high-end customization and cost-effective package services tailored to different customer needs, suitable for large enterprises, small and medium-sized enterprises as well as scientific research institutions;

(4) Industrialization implementation: Optimizing large-scale cultivation schemes to assist customers in rapid technology transformation and reduce implementation costs;

(5) Professional support: Staffed by a senior technical team, offering whole-process one-on-one guidance and comprehensive after-sales technical support.